The Genetics Of Breast Cancer

Every woman runs the risk of getting breastThey are born with this abnormal gene. 85
cancer and as she gets older, the chances arepercent to 90 percent of breast cancers are as a
greater. The chances of a woman getting breastresult of acquired genetic abnormalities.
cancer is 14 percent or one in every eightThe chances that an individual will have an
women, when you consider a lifetime of aabnormal breast cancer gene are:
woman, assuming she lives up to the age of. If a single individual in the family suffers from
about 90 years. If you consider that in yourboth ovarian and breast cancer.
lifetime of 90 years, the chances are 14 percent. If on either the individual's mother's or father's
that you will get the disease. The good news isside sisters, aunts, mother or grandmothers have
that 86 percent you will not get the disease.had breast cancer diagnosed before the age of
How does genetics affect your chances of50.
getting breast cancer?. A male in the individual's family has had breast
Most of the inherited cases of breast cancer havecancer.
been linked with the two genes Breast Cancer. The women in the individual's family have had
gene 1 (BRCA1) and Breast Cancer gene 2cancer in both their breasts.
(BRCA2). These two genes play a role in keeping. If the individual is from Eastern Europe.
the breast cells growing normally and preventingIf an individual's mother or father has an abnormal
any cancerous cell growth. However, abnormalbreast cancer gene, the chances of the gene
BRCA 1 and BRCA2 gene increase an individual'spassing onto that individual is 50 percent. The
risk from breast cancer. These genes usuallychances of the individual passing it onto their
account for almost up to 10 percent of all breastchildren is 25 percent, provided the father does
cancers.not have an abnormal gene. It does not
Whilst a majority of women who get breastnecessarily mean that all family members will have
cancer have no family history of the disease, thean abnormal gene if one family member has it.
women who are diagnosed with the disease andMen and breast cancer
also have an abnormal BRCA1 or BRCA2 geneMen are at an increased risk from breast cancer
often are women with a family history of theif they inherit the abnormal breast cancer genes.
disease.Over a man's lifetime, the risk is about 6 percent,
These abnormal BRCA1 and BRCA2 genes canwhich is about 80 times more than for a man
either be acquired or inherited. Acquired is nonwith no abnormal breast cancer genes.
hereditary and the gene becomes abnormal as aResearch has also shown that men who have an
result of an error in how the gene reproduces,abnormal breast cancer gene are more likely to
wear and tear, exposure to toxic material,get prostate cancer than men who do not have
hormonal influence, diet, environmental factors orit. This abnormal gene also has the same
sometimes even unknown factors. Inherited fromincreased effect on cancer of the digestive tract
parent, that is one normal gene from one parentor on cancer of the skin.
and one abnormal gene from the other parent.