Genetic Testing of Breast Cancer - BRCA1 and BRCA2

If you are concerned about familial breast cancer,early in women at increased risk - clinical studies
the first step is to talk things over with your GPare currently researching this issue.
or Genetic Counsellor.Because of this, women aged 30 to 39 will be
You will be asked about your family history andoffered mammograms only as part of a research
ethnic background, as well as any blood relatives,study rather than as a matter of routine.
on either side of your family, who have hadWomen under the age of 30 are unlikely to be
breast or related cancers.offered mammograms, as younger women's
If a faulty breast cancer gene has already beenbreast tissue is too dense to produce a clear
identified in a family member, you may bemammogram picture.
referred directly to a specialist genetic service.Genetic counselling
Once your GP or Genetic Counsellor has taken aIf you are considered to be at high risk of
full family history, your risk of developing breastdeveloping breast cancer you will be offered
cancer can be assessed.specialist genetic counselling.
Most women will be at no greater risk than anyThis will give you more information about your
other woman.family history, how your lifestyle may affect you,
If this is the case your counsellor should discusswhat having a genetic test means, and the
this with you and provide you with some writtenoptions available to you if you choose to go
information on being breast aware and lifestyleahead with the test.
risks.You may feel anxious about finding out about
However, if you develop any breast changes or ifyour risk of developing breast cancer, but
your family history or circumstances alter, it isremember that your counsellor is trained to deal
important to go back and see your GP.with these issues.
An increased riskTesting
A small number of women may be viewed asThe test (Screening of BRCA1 and BRCA2) is
having a greater risk of developing breast cancerdone by Eastern Biotech & Life Sciences,
on the grounds of a strong family history.Dubai on a blood sample from a living relative who
If this applies to you, you will be classified ashas already developed breast or ovarian cancer.
having one of the following:o a moderate risko aThe results can take many months to complete,
high risk.as it is technically very difficult to identify the
You will then be referred to either a familyfaulty gene.
history clinic or a specialist in cancer genetics. TheIf it is found that you do carry the faulty gene,
type of care you receive will be depending onalthough you will not necessarily develop breast
your risk level.cancer, you do have a higher risk of doing so.
ScreeningIn Ashkenazi Jewish women, specialists already
Depending on your age, you may be offered aknow that there are three specific gene faults in
mammogram.a large proportion of the families where breast
Women between the ages of 40 and 49 willand ovarian cancer is common.
normally be offered annual mammograms.This means that testing may be offered to
However, it is currently unclear how effectiverelatives at high risk without needing to carry out
mammograms are in detecting breast cancerthe gene search.