| Digital mammography, where the detector uses | | | | whereby overlying normal tissues can mask the |
| digital technology, has been shown to be superior | | | | pathologies of interest. We have seen how |
| to conventional analog screen-film mammography, | | | | tomosynthesis imaging, because it is 3-D, helps |
| especially in the difficult-to-image denser breasts. | | | | improve visibility. It is thus natural to try and |
| However, the long-term promise of digital | | | | combine these two techniques into what is known |
| mammography is probably its use as an enabler | | | | as contrast enhanced breast tomosynthesis. This |
| of more advanced imaging methods. One of | | | | means 3-D imaging of the contrast agent. The |
| these is known as tomosynthesis. Breast | | | | iodinated contrast agent is administered in the |
| tomosynthesis is a three-dimensional (3-D) digital | | | | conventional way, and instead of performing 2-D |
| mammography imaging technology that has | | | | digital mammography, the patient is imaged using |
| shown significant early promise in improving | | | | the breast tomosynthesis machine. The radiologist |
| mammography's accuracy. | | | | will then review the sequence of 3-D images of |
| Breast tomosynthesis consists of taking multiple | | | | the drug's flow into and out of the breast tissue. |
| images at multiple angles about a stationary | | | | Contrast enhanced breast tomosynthesis is similar |
| compressed breast, with a total radiation dose | | | | to another imaging modality that is increasingly |
| similar to conventional mammography. The images | | | | becoming more commonplace- breast MRI. In |
| are reconstructed into a 3-D image, similarly to | | | | breast MRI, the patient is given an injection of an |
| CT or MRI images. The value of the 3-D image is | | | | MRI contrast agent, and the patient undergoes a |
| tumors are less likely to be hidden amongst | | | | sequence of MRI images. Both methods are |
| normal tissues as they are in a two dimensional | | | | looking for local contrast agent concentrations |
| (2-D) conventional mammogram. Early clinical trials | | | | that can be indicative of breast cancer. Both look |
| of tomosynthesis show the potential for both | | | | for washin and washout characteristics to try to |
| improved cancer detection and the reduction in | | | | differentiate benign from malignant pathologies. |
| the need for additional diagnostic imaging for | | | | And both image the contrast agents using 3-D |
| women who are subsequently found to be cancer | | | | technology. |
| free. | | | | For some great information on how to treat |
| Contrast mammography, as described here, is a | | | | Breast Cancer take a look at Breast Cancer |
| 2-D imaging modality. Thus, it suffers from the | | | | Information. |
| same limitations as conventional mammography, | | | | |