A Mini-Camera For The Treatment Of The Breast Cancers

With the interface between cancerology andprotocol of the "ganglion sentinel" within the
physics, the current technological projections toframework of the breast cancers. In practice, this
improve the assumption of responsibility oflast is detected thanks to the injection of a
cancers rest primarily on the development of newradioactive solution around the tumor. A
physical methods for tracking, the diagnosis andlymphoscintigraphy then makes it possible to
the clinical therapy. Among those, the techniquescount the ganglia and to obtain their precise
of medical imagery based on the use oflocalization. Lastly, the biopsy is traditionally carried
radioactive tumor tracers make important greatout in operating theatre suite using the probe
strides thanks to the development of new andmeter of radioactivity which makes it possible to
specific molecules. Beyond the instrumentation,the surgeon to check the position of the "ganglion
this multi-field research extends to the clinicalsentinel" before the incision, to identify it in the
aspect and aims at establishing a methodologyoperational wound and finally, after excision, to
adapted in order to evaluate the advantage ofconfirm the absence of any residual radioactivity.
the apparatus on patient. It is in this context thatThe clinical evaluation of camera POCI associating
researchers of laboratory IMNC set up anfor the first time of the researchers of
interdisciplinary group of research with doctors ofin2P3-CNRS and the AP-HP rests on a double
the hospital Tenon (Paris) whose work allowed thestudy: to prove its equivalence compared to the
development of a hospital Program for clinicalgamma-cameras standards and to establish its
research (PHRC), national program which tallies theinterest in operating theatre suite in order to
clinical evaluation of imager POCI on 200 patients.identify the "ganglia sentinels" not detected by the
POCI, a new device of medical imagery-probe. Begun in January 2006 with the agreement
Within the framework of the surgical treatmentfrom the Consultative Committee from protection
of cancer, probes acting as of the meters offrom the people in biomedical research (CCPPRB)
radioactivity were introduced in operating theatreand that from the French Agency from medical
suite to assist the surgeon in real time during thesafety from the products from health
ablation of the beforehand radio-marked tumors.(AFSSAPS), this clinical study includes 200 patients.
This technique of radio guidance gives access theAfter examination of a hundred patients with
precise localization and the complete ablation ofcamera POCI as well in service of nuclear
tumor fabrics. It is to reinforce this technique thatmedicine as in operating theatre suite, the first
the team "Imagery and Modeling in Cancerology"results are extremely encouraging.
of the IMNC undertook the development of aSeveral groups of research, in particular in North
new generation of gamma-camera miniaturizedAmerica, in Japan and in Italy, were directed
for the assistance with the chirurgical treatmenttowards the development of portable
of cancer called POCI. It is about a particularlygamma-cameras specifically dedicated to
innovative application of the instrumentalper-operational detection. It is in this context of
developments used in fundamental physics. Withstrong international competition that the team of
13 cm2 of fields of sight and reduced dimensions ,the IMNC remains the only one today to have
this imager was designed to be easily positioned inevaluated, in operating theatre suite and on a
contact with the operational wound in order tosignificant number of patients, a system of
locate the tumor lesions radio-marked during theimagery miniaturized for the assistance with the
surgical operation .surgical treatment of cancer.
Imager POCI is currently evaluated via the